COST Action Infogut
Our laboratory is actively involved in the COST Action CA23110 INFOGUT, which aligns with the European 3R principles aiming to reduce animal use in research and promote the development of alternative in vitro strategies. The goal of this action is to bring together academic experts, industrial partners, and regulatory agencies to harmonize, optimize, and disseminate in vitro models that replicate human or animal intestinal microbiota. By contributing to this initiative, we support collaborative research and the development of innovative solutions to better understand microbiota-health interactions.
Our team's contribution
Action Vice Chair : Stéphanie BLANQUET-DIOT |
| WG1 - Review of existing in vitro human colon models and harmonized guidelines |
| Members Sylvain DENIS Ophelie URIOT |
| WG2 - Extension to other gut compartments and host interactions |
| Elora FOURNIER Task 2.1 Co-leader - Connection to upper GI tract Ludovica MARINELLI Task 2.2 Co-leader - Coupling with host cells Members Chloe BELTRAMO Auriane BRON Ingrid COUTURIER |
| WG3 - Extension to diseased situations |
| Lucie ETIENNE-MESMIN - Work Group Leader Charlotte DESCHAMPS Task 3.1 Leader - Overview on in vitro models adapted to reproduce gut microbiota dysbiosis associated to most common digestive pathologies (IBD, IBS, colon cancer…). Discuss the current limitations of these models in comparison to in vivo situations. Members Auriane BRON Ophelie URIOT |
| WG4 - Data science and data management |
| Member Claude DURIF |
Book of conference proceedings : https://doi.org/10.6092/unibo/amsacta/8570
Infogut Website : https://infogut.eu/